منابع مشابه
The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal Development.
DenA/DEN1 and the COP9 signalosome (CSN) represent two deneddylases which remove the ubiquitin-like Nedd8 from modified target proteins and are required for distinct fungal developmental programmes. The cellular DenA/DEN1 population is divided into a nuclear and a cytoplasmatic subpopulation which is especially enriched at septa. DenA/DEN1 stability control mechanisms are different for the two ...
متن کاملChemoprevention by Euphorbia Neriifolia of DENA-induced Mouse Renal Carcinogenesis
Kidney cancer is the third most common malignancy of the genitourinary system account for 2 to 3 % of all cancers in men worldwide, with 130,000 new cases and 63,000 deaths from the disease occurring annually (Ferlay et al., 2004). Certain toxic chemicals and medicines can cause renal damage, are recognized as a toxicological problem. NNitrosodiethylamine (DENA) is the most important environmen...
متن کاملControl of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome
Deneddylases remove the ubiquitin-like protein Nedd8 from modified proteins. An increased deneddylase activity has been associated with various human cancers. In contrast, we show here that a mutant strain of the model fungus Aspergillus nidulans deficient in two deneddylases is viable but can only grow as a filament and is highly impaired for multicellular development. The DEN1/DenA and the CO...
متن کاملEffect of DENA induced hepatocarcinogenesis on neuroendocrine levels in male rats.
Hepatocarcinogenesis was induced in Sprague Dawley rats by injecting diethylnitrosamine (DENA); 150 mg/kg body weight, ip, a well known liver carcinogen and a mutagenic agent. Concurrent with the induction of hepatocarcinoma, psychological stress was also elicited from the changes in brain neurotransmitters. Noradrenaline and dopamine, the neurotransmitters of sympathetic system were estimated ...
متن کاملGIS-Based Landslide Susceptibility Mapping by AHP Method, A Case Study, Dena City, Iran
Slope instability research and susceptibility mapping is a fundamental component of hazard management in decreasing the risk of living with landslides. Landslide susceptibility is defined as the proneness of the terrain to produce slope failures and susceptibility is usually expressed in a cartographic way. The Dena city in Iran is a landslide prone zone because of its own characteristics inclu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Lapurdum
سال: 2003
ISSN: 1273-3830,1965-0655
DOI: 10.4000/lapurdum.1104